Cristiano Ronaldo scored a first-half goal for Manchester United in their opening game of the 2021/2022 UEFA Champions League campaign.
The Portuguese international needed just 13 minutes to score his third goal for Red Devils since joining from Juventus.
United was reduced to 10-men after right back Wan-Bissaka was issued a straight red card on the 36th minute.
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Young Boys came back stronger in the second half with Ngameleu grabbing an equalizer on 66 minutes.
The Swiss side left it late to grab a winner as substitute Theoson Siebatcheu scored on added time to spoil a second Champions League debut for Cristiano Ronaldo.